1 - 7 of 7 articles
Summary We assessed the efficacy of prolonged interferon‐α (IFN) therapy in children with chronic hepatitis caused by hepatitis delta virus (HDV) by treating 26 paediatric cases with IFN‐α2b(5 MU m‐2, then 3 MU m‐2 three times weekly for 12 (medium‐term group, MTG) or 24 months (long‐term group,...
Summary An individual's iron status may affect the response rate achieved with the use of interferon (IFN) as therapy for chronic viral hepatitis. A total of 27 patients with chronic hepatitis B viral infection, who had elevated serum ferritin levels, were randomized to receive either IFN 5 MU,...
Summary Haemodialysis patients often fail to respond to hepatitis B vaccination. In this pilot study, 15 patients previously non‐responsive to at least three 40 μg doses of hepatitis B vaccine were given 0.5, 5 or 10μg kg‐1 granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) subcutaneously...
Summary To determine the incidence of hepatitis C virus (HCV) infection in patients with alcoholic liver disease (AID), serum samples from 252 patients with AID were tested for anti‐HCV and HCV RNA. Serial sera of these patients were collected and stored under optimal conditions to allow exact...
Summary We present a patient with an unusual course of hepatitis B e antigen (HBeAg)‐negative chronic hepatitis B who had repeated reactivations of his disease progressing to cirrhosis with terminal liver failure. Each flare up presented like an acute hepatitis with very high titres of hepatitis...
Summary The hepatitis B virus (HBV) genome encodes a 154 amino acid protein termed X (HBx, hepatitis Bx protein), which is a promiscuous transcriptional activator of polymerase II and III promoters. HBx upregulates a wide range of cellular and viral genes and is thought to facilitate viral...
Summary Unravelling the role of interferon (IFN) in the treatment of chronic hepatitis B is complicated by many factors. Several mutant forms of hepatitis B virus (HBV) have recently been discovered; the most common of these is the precore mutant, characterized by hepatitis Be antigen (HBeAg)...
Read and print from thousands of top scholarly journals.
Continue with Facebook
Sign up with Google
Log in with Microsoft
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Sign Up Log In
To subscribe to email alerts, please log in first, or sign up for a DeepDyve account if you don’t already have one.
To get new article updates from a journal on your personalized homepage, please log in first, or sign up for a DeepDyve account if you don’t already have one.