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The concept of pharmacologic “class effects” exists across a broad range of medical products and is particularly pervasive with regard to cardiovascular agents. Evolution of the concept over the past two decades has shown the influence of physicians’ practice patterns, pharmaceutical...
Objectives The goal of this study was to determine the therapeutic efficacy of angiotensin-converting enzyme (ACE) inhibitors and beta-adrenergic receptor blockers in experimental chronic mitral regurgitation (MR), gaining knowledge using methods difficult to apply in humans.
Objectives This study evaluates the hemodynamic, bioenergetic and cytoprotective effects of urocortin (Ucn) in the isolated rat heart exposed to ischemia (I)/reperfusion (R).
Objectives We evaluated the incidence and predictors of sudden death after atrioventricular (AV) node ablation and pacemaker implantation.
Objectives This study planned to establish whether sympathetic hyperactivity exists in white-coat hypertension (WHT) in the clinical setting, relative to matched groups with normotension (NT) and untreated essential hypertension (EHT).
Objectives The study investigated the clinical significance and mechanism of orthostatic blood pressure (BP) dysregulation in elderly hypertensive patients.
Objectives We sought to study the expression of bradykinin type-2 receptors (BK-2Rs) in patients with heart failure (HF).
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