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OBJECTIVES This study was designed to compare the hemodynamic efficacy of nonsurgical septal reduction therapy (NSRT) by intracoronary ethanol with standard therapy (surgical myectomy) for the treatment of hypertrophic obstructive cardiomyopathy (HOCM). BACKGROUND Nonsurgical septal reduction...
OBJECTIVES We hypothesized that wall motion velocity during pre-ejection is proportional to the regional content of viable myocardium after reperfusion for acute myocardial infarction (AMI). BACKGROUND Pre-ejection wall motion consists of short and fast inward and outward movement towards and...
OBJECTIVES We sought to investigate wall shear rate (WSR) and brachial artery diameter (BAD) changes simultaneously and to determine whether any gender differences exist in arterial reactivity. BACKGROUND Wall shear rate/stress and arterial reactivity are rarely assessed at the same time....
OBJECTIVES This study was designed to examine whether the occurrence of left ventricular hypertrophy (LVH) in moderate to severe essential hypertension (EHT) was associated with alteration in peripheral sympathetic drive. BACKGROUND In hypertension, LVH is an independent predictor of increased...
OBJECTIVES The goal of this study was to determine the interaction between smoking and the glycoprotein IIIa P1 A2 polymorphism in patients admitted with non–ST-elevation acute coronary syndromes (ACS). BACKGROUND An increased incidence of the P1 A2 polymorphism in smokers presenting with...
OBJECTIVES The aim of this study was to determine the effect of angiotensin II type 1 (AT 1 ) receptor antagonists on pro-oxidant species observed in the pathogenesis of atherosclerosis. Parameters such as low-density lipoprotein (LDL) susceptibility, monocyte binding capacity, superoxide...
OBJECTIVES We tested the hypothesis that cardioprotection with ischemic preconditioning (PC) is lost in the aging, or senescent, heart. BACKGROUND Although infarct size reduction with PC has been documented in virtually all models, a purported exception to this paradigm is the aging heart, the...
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