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Background The effects of short-term enteral arginine supplementation on intestinal ischemia-reperfusion (IR) injury have been widely studied, especially the ischemic preconditioning supplementation. The aim of this study was to investigate the effects of long-term intra-duodenal supplementation...
Background Utilizing livers from donors after cardiac death could significantly expand the donor pool. We have previously shown that normothermic (37°C) extracorporeal liver perfusion significantly improves transplantation outcomes of ischemic rat livers. Here we investigate whether recovery of...
Background We have shown that partially major histocompatibility complex (MHC)-matched splenocytes can replace bone marrow (BM) and maintain skin grafts by establishing splenocytic chimeras. Our aim was to identify the population of splenocytes that are indispensible for switching from BM to...
Background As part of a larger study evaluating breast cancer care, we attempted to validate our matching strategies between the National Cancer Data Base (NCDB) and ACS National Surgical Quality Improvement Program (ACS-NSQIP).
Background Sphingosine-1-phosphate (S-1-P) is a bioactive sphingolipid released from activated platelets at sites of arterial injury that stimulates migration of smooth muscle cells (SMC). The kinase src is a significant focal point in transmembrane signaling. This study examines the role of src...
Background Gene therapy has attracted attention for its potential to treat several cardiovascular diseases. The use of adeno-associated viral (AAV) vectors to facilitate therapeutic gene transfer to suppress intimal hyperplasia is a promising concept. The objective of this study was to analyze...
Background Although well-differentiated liposarcoma (WD Lipo) is a low grade neoplasm with a negligible risk of metastatic disease, it can be locally aggressive. We hypothesized that survival for WD Lipo varies significantly based on tumor location.
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