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Journal of Physiology and Biochemistry

Subject Areas: Biochemistry; ; ;
Publisher: Springer Netherlands - Springer Journals
ISSN: 1138-7548
SJR: 52

Open Access

Journal Article

NCS-1 protein regulates TRPA1 channel through the PI3K pathway in breast cancer and neuronal cells

Sánchez, Julio C.; Alemán, Alexander; Henao, Juan F.; Olaya, Juan C.; Ehrlich, Barbara E.

2024 Journal of Physiology and Biochemistry

doi:10.1007/s13105-024-01016-z pmid:38564162

The physical and functional interaction between transient receptor potential channel ankyrin 1 (TRPA1) and neuronal calcium sensor 1 (NCS-1) was assessed. NCS-1 is a calcium (Ca2+) sensor found in many tissues, primarily neurons, and TRPA1 is a Ca2+ channel involved not only in thermal and pain...
Open Access

Journal Article

Fasting and fasting-mimicking conditions in the cancer immunotherapy era

Pio, Ruben; Senent, Yaiza; Tavira, Beatriz; Ajona, Daniel

2024 Journal of Physiology and Biochemistry

doi:10.1007/s13105-024-01020-3 pmid:38587595

Fasting and fasting-mimicking conditions modulate tumor metabolism and remodel the tumor microenvironment (TME), which could be exploited for the treatment of tumors. A body of evidence demonstrates that fasting and fasting-mimicking conditions can kill cancer cells, or sensitize them to the...

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