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Abstract To investigate the absorption of recombinant hirudin-2 (rHV2) after oral administration to rats and its possible absorption mechanism, a series of experiments were carried out. The degradation of 125 I-rHV2 in the luminal contents and variant mucosal subcellular fractions, as well as the...
Abstract Calcimimetic compounds, which activate the parathyroid cell Ca 2+ receptor (CaR) and inhibit parathyroid hormone (PTH) secretion, are under experimental study as a treatment for hyperparathyroidism. This report describes the salient pharmacodynamic properties, using several test systems,...