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Abstract Because neutrophil proteinases such as elastase and cathepsin G are considered to play a major role in inflammatory tissue damage, the microcirculatory effect of the serine proteinase inhibitor (serpin) Lex032 after ischemia/reperfusion (I/R)-induced pancreatitis was investigated. Lex032...
Abstract The aims of the study were to characterize the rate and extent of the rebound effect after abrupt cessation of a chronic exposure of l -propranolol in spontaneous hypertensive rats, using exercise-induced tachycardia as a pharmacodynamic endpoint. Thirty-two spontaneous hypertensive rats...
Abstract The contribution of 5-hydroxytryptamine (serotonin; 5-HT) acting at 5-HT 3 receptors to fast excitatory postsynaptic potentials (fEPSPs) and the properties of 5-HT 3 receptors in the guinea pig small intestinal myenteric plexus were investigated using electrophysiological methods. In 11%...