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10.1002/jps.2600801014.abs In this study, simple bootstrap techniques are combined with the extended Hansen solubility approach to calculate biases, standard errors, and confidence limits of the partial solubility parameters and to obtain bias‐corrected values for these solubility parameters....
10.1002/jps.2600801018.abs The polymorphism of (E)‐6‐(3,4‐dimethoxyphenyl)‐1‐ethyl‐4‐mesitylimino‐3‐methyl‐3,4‐dihydro‐2(1H)‐pyrimidinone (FK664; 1) was characterized by using X‐ray powder diffractometry, differential scanning calorimetry (DSC), and IR spectroscopy....
10.1002/jps.2600801013.abs Quantitative structure‐activity relationships of the metabolism of drugs by uridine diphosphate (UDP)‐glucuronosyltransferase have been investigated. It is observed that most of the variation in the rate of glucuronidation of phenols, thiols, and some other...
10.1002/jps.2600801016.abs Two polymorphs of carbamazepine that melt at 176 and 189° and are known to be enantiotropic have been characterized more fully than in previous reports. For the first time, a value for the heat of fusion (29.3 kJ/mol) of the lower melting form is estimated, even though...
10.1002/jps.2600801005.abs The purpose of this investigation was to determine the effect of body temperature on the pharmacodynamics (convulsant activity) of pentylenetetrazol (PTZ). Rats received an iv infusion of PTZ until the onset of maximal seizures, at which time samples of cerebrospinal...
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