Within the last year
Within the past 3 years
1 - 10 of 46 articles
10.1002/jps.2600710426.abs A series of 1,4‐bis(4‐guanylphenylethyl)benzenes, including masked amidines in which the guanyl function is incorporated into a heterocyclic ring, were prepared for screening as potential antitrypano‐somal agents. Some of these compounds were active against...
10.1002/jps.2600710421.abs The partition coefficient between tissue and blood used in physiologically‐based pharmacokinetic modeling analysis was investigated using the concept of clearance. New equations were derived and compared with previously reported equations in constant intravenous...
10.1002/jps.2600710409.abs To develop a parenteral solution of relatively water‐insoluble metronidazole (2‐methyl‐5‐nitro‐1H‐imidazole‐1‐ethanol), its phosphate ester was synthesized via two routes. One route utilized 2‐cyanoethyl phosphate and the other utilized pyrophosphoryl...
10.1002/jps.2600710408.abs Data are presented showing that the anomalous dissolution behavior of ticrynafen in simulated intestinal fluid without enzyme is due to the presence of potassium ions in the dissolution medium. Solubility studies indicate that an insoluble 1:1 complex is formed between...
Save this article to read later. You can see your Read Later on your DeepDyve homepage.
To save an article, log in first, or sign up for a DeepDyve account if you don't already have one.
Sign Up Log In
To subscribe to email alerts, please log in first, or sign up for a DeepDyve account if you don't already have one.
Read and print from thousands of top scholarly journals.
Sign up with Facebook
Sign up with Google
Already have an account? Log in
To get new article updates from a journal on your personalized homepage, please log in first, or sign up for a DeepDyve account if you don't already have one.