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10.1002/jps.2600690712.abs A high‐performance liquid chromatographic method for the analysis of oxaprozin in the presence of ketoprofen (the internal standard) was developed. Sample preparation involved macro‐ and microextraction procedures. An octadecylsilane reversed‐phase system with an...
10.1002/jps.2600690721.abs The quantitative analysis of edetate disodium in nonprescription eyewash and ophthalmic solutions is described. The method involves differential pulse polarography using a dropping mercury electrode. A known concentration of cadmium or zinc is added to a buffer in a...
10.1002/jps.2600690707.abs A semiquantitative assessment of esterase and deaminase distributions in hairless mouse skin was performed in vitro. The enzyme activities were quantified using 3H‐vidarabine and its 5′‐valerate as the substrates. Full‐thickness skin of the hairless mouse was...
10.1002/jps.2600690719.abs The adsorption of tetracycline by clays commonly used in pharmacy can be predicted if the identity and character of the commercial clay sample are established. X‐ray diffraction, IR spectroscopy, and chemical analysis were used to identify the clay component and any...
10.1002/jps.2600690720.abs The chemical shifts in the Fourier transform 13C‐NMR spectrum of ajmaline were assigned from consideration of the acetylation shifts and multiplet splitting in the off‐resonance decoupled spectrum. On the basis of the assigned signals, the changes of chemical shifts...
10.1002/jps.2600690706.abs The permeation behavior of 3H‐vidarabine (3H‐9‐β‐D‐arabinofuranosyladenine) and 14C‐n‐pentanol through different strata of hairless mouse skin was studied using a diffusion cell at 37° under steady‐state conditions. Partition coefficients for the skin...
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