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10.1002/jps.2600670926.abs The relative bioavailability of 400‐mg meprobamate tablets manufactured by 11 different firms was evaluated in two groups of healthy male subjects. Each group of six subjects received a reference standard product and five test products given at 1‐week intervals....
10.1002/jps.2600670943.abs An assay for gold in whole blood of arthritis patients was developed using the graphite furnace atomic absorption spectrophotometer. This method involves no pretreatment of the whole blood except for simple dilution, thereby eliminating some variables and saving...
10.1002/jps.2600670920.abs The preservation of solublized and emulsified disperse systems against microbial spoilage depends on the free (unbound) preservative concentration in the aqueous phase and the capacity of the system. The capacity may be defined as the system's ability to resist losses...
10.1002/jps.2600670935.abs Data are presented for selective demethylation of eight polymethoxyxanthones with aqueous piperidine. Clarification and rationalization of the present and previous observations are made. The mechanism is defined in terms of both resonance effects and steric factors.
10.1002/jps.2600670937.abs Twenty aromatic alcohols and thiols were derivatized by reaction with 3‐chloro‐1,2‐benzisothiazole 1,1‐dioxide. The resulting 3‐substituted 1,2‐benzisothiazole 1,1‐dioxides were tested against Staphylococcus aureus, Salmonella typhosa, and Aspergillus...
10.1002/jps.2600670925.abs 17β‐Acetoxy‐2α‐chloro‐3‐(p‐nitrophenoxy)imino‐5α‐androstane (I) is a lipophilic steroid with postimplantive antifertility activity in laboratory animals. The bioavailability of micronized I from solutions and suspensions was compared in four groups of...
10.1002/jps.2600670942.abs A spectrophotofluorometric assay for coralyne sulfoacetate was developed. Coralyne was extracted from serum samples with n‐butyl alcohol, and the drug concentrations were determined fluorometrically at 475 nm when the extract was excited at 325 nm. A biphasic serum...
10.1002/jps.2600670945.abs Series of 4‐arylsulfonylmethyl‐1,2,3‐selenadiazoles, 4‐(1‐arylsulfonylethyl)‐1,2,3‐selenadiazoles, and 4‐alkyl (or aryl) ‐5‐arylsulfonyl‐1,2,3‐selenadiazoles were synthesized. 4‐(3‐Pyridyl)‐5‐phenylsulfonyl‐1,2,3‐selenadiazole...
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