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10.1002/jps.2600650924.abs A sensitive and specific high‐performance liquid chromatographic procedure for the determination of chlorpropamide or tolbutamide in plasma in the presence of their metabolites is described. The ether extract of acidified plasma is redissolved in the mobile phase, 17%...
10.1002/jps.2600650913.abs The optimum conditions for the polarographic reduction of some tetracycline antibiotics were studied. A boric acid‐sodium borate buffer provided the best conditions for the electroreduction of tetracycline, oxytetracycline, chlortetracycline, and demeclocycline....
10.1002/jps.2600650920.abs Results of studies carried out in rats for model compounds, D‐(—)‐mandelic acid, benzoylformic acid, and some of their para‐alkylated homologs, showed that their biological half‐lives determined from the elimination phase of urinary excretion data were longer...
10.1002/jps.2600650938.abs The chloroform extract of Vauquelinia corymbosa Correa has shown activity against the P‐388 lymphocytic leukemia test system. The constituents responsible for this activity were identified as uvaol, ursolic acid, and betulinic acid. Their identity was proven by...
10.1002/jps.2600650927.abs A highly potent cardiotonic polypeptide, anthopleurin‐A, was isolated from the sea anemone, Anthopleura xanthogrammica (Brandt), using solvent partition, gel permeation chromatography, and cation‐exchange chromatography. It is a pure basic polypeptide with a...
10.1002/jps.2600650932.abs The development of order during the aging of aluminum hydroxide gel prepared by the reaction of aluminum chloride and ammonium hydroxide to a final pH of 7.0 can be monitored by differential thermal analysis. The loss of acid reactivity upon aging is accompanied by an...
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