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10.1002/jps.2600630811.abs Permeation experiments were used to look for interactions between chlordiazepoxide and some common excipients, nutrients, and surfactants. No effect on the permeability coefficient was observed in the presence of starch, calcium hydrogen phosphate, gelatin, lactose,...
10.1002/jps.2600630839.abs The interaction of theophylline with sodium benzoate was examined by NMR to understand the mode of interaction. Chemical shifts of theophylline protons were determined as a function of sodium benzoate concentration in D2O at 30°. Several different concentrations of...
10.1002/jps.2600630846.abs A mixture of commercial boron trifluoride etherate and an alcohol functions as an effective reagent in the direct esterification of a number of aromatic carboxylic acids bearing additional functional groups such as —OH, —NH2, >CO, —O—, and —S—, either...
10.1002/jps.2600630835.abs Model solutions of certified dyes (FD&C Blue No. 2, FD&C Yellow No. 5, and FD&C Yellow No. 6) were exposed, alone or with added selected excipients, in a fadeometer to accelerate light‐induced color fading. At predetermined intervals, the solutions were tested...
10.1002/jps.2600630808.abs The effect of sodium salicylate on the metabolism of 3T6 fibroblasts treated with the lathyrogen β‐aminopropionitrile was studied. A 5 mM concentration of the lathyrogen and/or 0.5 mM sodium salicylate was used to study proliferation, collagen synthesis, and...
10.1002/jps.2600630820.abs An increase in extracted radioactivity was found when the aromatic aldehydes 2‐nitrobenzaldehyde or pyridine‐4‐carbox‐aldehyde were incubated with catechol‐O‐methyltransferase in the presence of 14C‐methyl‐S‐adenosylmethionine and dopamine or...
10.1002/jps.2600630813.abs Six healthy male subjects were given 0.5 mg of digoxin on three separate occasions in the form of an elixir and two different commercially available brands of compressed tablets. Blood levels were measured by a radioimmunoassay technique at various time intervals up to...
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