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Purpose: Nearly all eye drops contain preservatives to decrease contamination. Nonpreservatives such as disodium-ethylene diamine tetra-acetate (EDTA) and phosphate-buffered saline are also regularly added as buffering agents. These components can add to the toxicity of eye drops and cause ocular...
Purpose: Azithromycin is an azalide class of antibiotic with pharmacodynamics that have made it a valuable agent in the treatment of soft tissue infections. In ophthalmology, oral administration of azithromycin has been proven effective for the treatment of trachoma. However, topical formulations...
Purpose: The aim of this study was to report successful treatment of Paecilomyces lilacinus keratitis with voriconazole. Method: Case series. Results: Two patients with history of penetrating keratoplasty (PKP) presented with progressive P. lilacinus keratitis. Initial medical treatment failed to...
Aims: Timolol is used topically for the treatment of glaucoma and metabolized by cytochrome P450 (CYP) 2D6 in the liver. The aim of this study is to test the hypothesis that CYP 2D6 single-nucleotide polymorphism (SNP) is associated with drug effects of ophthalmic timolol. Methods: A total of 133...