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Fruit flies jump when startled by a sudden decrease in light intensity. We show that this visually-induced jump response in Drosophila melanogaster is sensitive to three general anesthetic agents: halothane, enflurane, and methoxyflurane. The concentration of anesthetic required to inhibit this...
Previous studies showed an association between the Ahr locus on Chr 12 and a maj or gene, Aspl , that influences susceptibility to audiogenic seizures (AGS) in mice. Although the association was thought to involve close linkage, a pleiotropic effect of the Ahr locus on AGS susceptibility was not...
Sites in the brain that show functional, sexual dimorphism in courtship behavior have been mapped at high resolution in male/female mosaics of Drosophila melanogaster. The sex mosaics were produced by enhancer-trap expression of GALA driving the female-spliced form of the transformer gene ( tra...
Messenger RNA editing of transcripts encoding voltage-sensitive ion channels has not been extensively analyzed - least of all in Drosophila , for which several channel-encoding genes are known. Previous sequence studies of D. melanogaster's cacophony gene, which encodes an α1 calcium-channel...
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