Within the last year
Within the past 3 years
1 - 6 of 6 articles
Interferon- β (IFN- β ) is biologically unstable under physiologic conditions in vitro and is cleared rapidly from the bloodstream on administration in vivo . In the present study, we demonstrate that a soluble recombinant form of the type I IFN receptor subunit, sIFNAR-2, can neutralize the...
To test the hypothesis that HIV infection brings about an alteration in the immune response to tuberculosis (TB), mycobacterial antigen-induced production and plasma levels of the inflammatory cytokine interferon- γ (IFN- γ ) and its regulatory cytokines interleukin-12 (IL-12), IL-18, and IL-10...
Type I interferons (IFNs) are potent regulators of both innate and adaptive immunity. All type I IFNs bind to the same heterodimeric cell surface receptor composed of IFN- α receptor (IFNAR-1) and IFN- α / β receptor (IFNAR-2) polypeptides. This study revealed that type I IFN receptor levels...
Ginseng radix, the dried root of Panax ginseng C. A. Meyer, has been shown to enhance the ability to resist microbial infections. Proinflammatory cytokines, such as tumor necrosis factor- α (TNF- α ), interleukin-1 β (IL-1 β ), IL-6, and interferon- γ (IFN- γ ) are produced by macrophages...
Using oligonucleotide microarrays, we have examined the expression of 22,000 genes in peripheral blood cells treated with pegylated interferon- α 2b (PEG-IFN- α ) and ribavirin. Treatment with ribavirin had very little effect on gene expression, whereas treatment with PEG-IFN- α had a dramatic...
In this report, the mechanism through which interferon- γ (IFN- γ ) regulates the expression of nitric oxide synthase (NOS-1) in neurons was examined. We have shown previously that IFN- γ treatment of cells results in a two log inhibition of vesicular stomatitis virus (VSV) production. This...
Save this article to read later. You can see your Read Later on your DeepDyve homepage.
To save an article, log in first, or sign up for a DeepDyve account if you don't already have one.
Sign Up Log In
To subscribe to email alerts, please log in first, or sign up for a DeepDyve account if you don't already have one.
Read and print from thousands of top scholarly journals.
Sign up with Facebook
Sign up with Google
Already have an account? Log in
To get new article updates from a journal on your personalized homepage, please log in first, or sign up for a DeepDyve account if you don't already have one.