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A Moloney-derived retrovirus containing both LacZ and NeoR genes (G1BgSVNa from Genetic Therapy, Inc.), was used to transduce human and murine bone marrow stromal cells. Different kinds of stromal cells that were able to support hematopoiesis were transduced by incubation for 24 h in the presence...
The purpose of this study was to determine the effectiveness of second mobilization strategies in patients who yielded <2.5 x 10 6 CD34+ PBSC/kg after initial mobilization. Repeat mobilization attempts were made with chemotherapy and G-CSF ( n = 61) or G-CSF alone ( n = 58) in patients who failed...