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The division of a protein interaction network into biologically meaningful modules can aid with automated detection of protein complexes and prediction of biological processes and can uncover the global organization of the cell. We propose the use of a graph summarization (GS) technique, based on...
Recent studies demonstrate that the peptides in the serum of cancer patients that are generated ( ex vivo ) as a result of tumor protease activity can be used for the detection and classification of cancer. In this paper, we propose the first formal approach to modeling exopeptidase activity from...
Protein complexes are functional units in the cell whose formation is regulated by a number of mechanisms. Previous studies have suggested that transcriptional co-regulation of protein components play a minor role in assembly of individual complexes. Recent developments in experimental approaches...