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10.1002/jcb.240260203.abs In order to better understand the mechanism by which changes in the fatty acid composition of cellular lipids occur in leukemia cell lines induced to differentiate, the activity of the first enzyme of fatty acid biosynthesis, acetyl‐CoA carboxylase (EC 188.8.131.52) was...
10.1002/jcb.240260204.abs Cellular oncogenes and their activated and retrovirus‐coded counterparts play an important role in cellular regulation. Here the relationship between such oncogenes and the genes coding for the transforming proteins of the papovaviruses, polyoma viruses, and simian...
10.1002/jcb.240260208.abs The effect of neonatal deafferentation on the expression of a neuronal cell surface heparan sulfate proteoglycan (HeS‐PG) was investigated in the developing rat superior cervical ganglion. Two monoclonal antibodies, one directed against the core protein of HeS‐PG,...
10.1002/jcb.240260207.abs One of the major problems in developmental biology concerns how differential gene activity is regionally controlled. One approach to this problem is the use of mesenchyme specification of epithelial‐specific gene expression, such as, during tooth morphogenesis or lung...
10.1002/jcb.240260202.abs The murine macrophage‐derived cell line P388D1 secretes the lymphokine inter‐leukin 1 (IL‐1) when stimulated by a variety of agents. When stimulated by bacterial lipopolysaccharide (LPS) the cells release IL‐1 in both high and low molecular weight (m.w.) forms....
10.1002/jcb.240260205.abs The transforming protein of Rous sarcoma virus (RSV) typically appears as a single phosphorylated polypeptide designated pp60v‐src, pp60v‐src possesses a protein kinase activity specific for tyrosine residues on select protein substrates. Treatment of...
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