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Background: We have previously shown that angiotensin II type 1 receptor blockers induce cardioprotection and upregulate angiotensin II type 2 receptor during in vivo postischemicreperfusion in dogs. Whether angiotensin II type 1 receptor blockers upregulate angiotensin II type 2 receptors in...
Background: Carvedilol, a ॆ-blocking agent with ॅ-blocking properties is now widely used for the treatment of congestive heart failure. In addition to its ॆ-adrenergic receptor blockage, antiapoptotic effects have been demonstrated in experimental animals. Objective: The cardioprotective...
Background: ॆ-Blocker therapy is now standard therapy for patients with stable heart failure; however, fluid-overloaded, New York Heart Association Class IV patients tolerate ॆ-blockers poorly. Amiodarone, a drug with antiadrenergic effects, has been shown to improve survival for patients...
Objective: Flaxseed oil has very high content of ox-linolenic acid (C18:3n-3, omega-3 n-3 fatty acid). Based on the usefulness of n-3 fatty acid in fish oil against cardiovascular diseases, flaxseed oil is marketed as a health food. The n-3 fatty acid in flaxseed oil is different than that of...
Electrical storm is defined as a recurrent episode of hemodynamically destabilizing ventricular tachyarrhythmia that usually requires electrical cardioversion or defibrillation. We describe three cases presenting with electrical storm under differing circumstances: (1) a 57-year-old man with...
Background: Aortic stenosis is an inflammatory process, as evidenced by increased tissue expression and serum levels of various endothelial cellular adhesion molecules. Aortic stenosis and atherosclerosis have many risk factors in common, including hypercholesterolemia. In atherosclerosis,...
Background: Magnesium has recently been shown to inhibit acute stent thrombosis in animal models. This study tested the feasibility of magnesium administration in patients undergoing nonacute percutaneous coronary intervention with stent implantation. Methods: Twenty-one patients undergoing...
Objective: The study analyzed the role of differentvariables that determine long-term sinus rhythm maintenance inpatients with persistent atrial fibrillation who are treated withamiodarone. Background : It has been recognized that different factors influence long-term sinus rhythm preservation...
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