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This Viewpoint discusses the appropriateness of existing US Food and Drug Administration regulatory pathways for artificial intelligence (AI) and machine learning (ML) software in health care, and proposes a lifecyle-based framework given the iterative nature of AI/ML algorithms, including...
This Viewpoint reviews evidence for the benefits of polypills, corrects misconceptions about what they are and where and in whom they should be used, and outlines uncertainties that should be accounted for in strategies and research to increase their use.
Key PointsQuestionHow can physicians identify patients who are most likely to have hip osteoarthritis (OA)?
FindingsThe most useful findings for identifying patients with hip OA are squat causing posterior pain, groin pain on passive abduction or adduction, abductor weakness, and decreased...
This JAMA Patient Page describes coronary microvascular dysfunction and the procedures for testing for this condition.
This Viewpoint discusses the conditions that need to be in place for the wealth of patient data available in electronic health records to be converted into useful prediction scores usable by clinicians to make clinical decisions.
A 40-year-old woman with Graves disease presented with abdominal pain and constipation. Thyroid-stimulating hormone was undetectable and physical examination revealed a tender midline abdominal mass. Three months earlier she was evaluated for 3 to 4 months of amenorrhea, and a urine human...
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