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Key PointsQuestionIn adults in whom weaning from invasive mechanical ventilation is difficult, does early extubation using a protocolized noninvasive weaning regimen reduce the time to liberation from ventilation compared with protocolized invasive weaning?
FindingsIn this randomized clinical...
This Medical News article discusses a recently discovered association between time of year and cognitive performance even in people with Alzheimer disease.
ImportanceExcessive alcohol use is one of the most common causes of premature mortality in the United States. From 2006 to 2010, an estimated 88 000 alcohol-attributable deaths occurred annually in the United States, caused by both acute conditions (eg, injuries from motor vehicle collisions)...
Key PointsQuestionCan a consumer-targeted, pharmacist-led educational intervention reduce prescriptions for inappropriate medication among community-dwelling older adults?
FindingsIn this cluster randomized trial that included 489 older adults, the percentage achieving discontinuation of a...
This Viewpoint explains how group purchasing organizations (GPOs) – companies that purchase devices, supplies, and medication from multiple manufacturers and serve as single supply sources for hospitals and medical centers – contribute to supply shortages, higher prices, and limited product...
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