1 - 10 of 33 articles
Abstract Importance Postmenopausal status coincides with increased risks for chronic conditions such as heart disease, osteoporosis, cognitive impairment, or some types of cancers. Previously, hormone therapy was used for the primary prevention of these chronic conditions. Objective To update...
This Viewpoint discusses the unique challenges of crafting meaningful advance directives for patients with dementia and proposes a framework that accounts for changes in goals of care that might occur along the continuum of cognitive decline.
Results from the first phase 1 clinical trial investigating a preventive messenger RNA (mRNA) vaccine are in and the outlook for this alternative to inactivated vaccines is promising. In the proof-of-concept nonrandomized rabies vaccine trial funded by German pharmaceutical company CureVac, mRNA...
Several years ago we called attention to the banana as an undervalued source of nutriment.1 The defense of this fruit, which ought to be available at comparatively low cost in times of normal commerce and transportation facilities, almost invariably provokes protests from persons who maintain...
To the Editor Dr Juch and colleagues1 found that radiofrequency denervation plus exercise provided no clinically significant improvement compared with exercise alone, using a minimal clinically important difference (MCID) of at least 2.0 points on an 11-point numeric rating scale for low back...
A patient who doesn't speak English lies in bed, looking up at doctors who don't speak Spanish, who point their fingers at the patient’s body, chest, belly, and ask the only question they can: “¿tienes dolor?” We’ve all seen this, more or less. Yes or no—that's the entire story this patient is...
This Arts and Medicine essay explores the relevance of writer and artist William S. Burroughs to clinical medicine, and his importance to the author’s career as a Parkinson disease researcher.
This Medical News article discusses whether sedentary lifestyles contribute to this increasingly prevalent degenerative joint disease.
This Medical News article discusses the promise and challenges of CAR-T therapies.
Most of the more than 50 000 genetic changes currently associated with human diseases are point mutations, the swap of one DNA base pair for another. Now, researchers at Harvard University and the Broad Institute have developed a genome editing technology called base editing that changes one DNA...
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