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Key PointsQuestionIs there any diminution in 10-year overall survival for women with cT1-2N0 breast cancer and metastases to 1 or 2 sentinel lymph nodes undergoing breast-conserving surgery, whole-breast irradiation, and adjuvant systemic therapy treated with sentinel node dissection alone...
In this Viewpoint, 2017 Lasker-DeBakey Clinical Medical Research Award winners Douglas Lowy and John Schiller discuss the development of the virus-like particle technology that was used to create the human papillomavirus vaccine to prevent cervical cancer and other diseases.
Key PointsQuestionDoes the clinical benefit of lowering low-density lipoprotein cholesterol (LDL-C) levels depend on how LDL-C is lowered?
FindingsIn a mendelian randomization analysis of an individual-participant data meta-analysis that included 102 837 participants, combined exposure to...
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