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Cetuximab and Stage III Colon Cancer Survival A combination of leucovorin, fluorouracil, and oxaliplatin (FOLFOX) is standard therapy following resection of stage III colon cancer. In a multicenter randomized trial that involved 2686 patients with resected stage III colon cancer, Alberts and...
Two compounds that block certain calcium channels in the brain can suppress absence-like epilepsy seizures in rats, report researchers at the University of British Columbia, in Vancouver, Canada, and colleagues (Tringham E et al. Sci Transl Med. 2012;4:121ra19). In humans, most absence or...
Warm and sunny energy projects from The Sun Through the Trees (cover), ready to uplift and cheer a long winter's weary heart. Charles Burchfield (1893-1967), melancholic in personality for most of his life, experienced an epiphany of sorts in 1917, calling it his “Golden Year.” The Sun Through...
Patients younger than 60 years who have diabetes should be routinely vaccinated against hepatitis B virus, and physicians should consider hepatitis B vaccinations for older patients with diabetes, according to new recommendations from advisors to the US Centers for Disease Control and Prevention...
Edited by C. Robert Bernardino 228 pp, 269 illustrations, $79 Philadelphia, PA, Wolters Kluwer/Lippincott Williams & Wilkins, 2011 ISBN-13: 978-1-6091-3705-2 As the title implies, The Yale Guide to Ophthalmic Surgery is intended for anyone interested in ophthalmology or the various aspects of...
To the Editor: Dr Nauman and colleagues1 presented data from a large Norwegian cohort studied twice 10 years apart (Nord-Trøndelag County Health Study [HUNT-1 and HUNT-2]) on the association of changes in resting heart rate (RHR) with mortality from ischemic heart disease. The authors found that...
In Reply: Drs Nagamatsu and Yamashita suggest important possible determinants of perceptions of appropriateness of care. However, in keeping with our study's aim, we sought to collect subjective perceptions from bedside clinicians. Perceived inappropriateness of care ranged between 8% and 49%...
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