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Mice lacking a protein found in the synapses or spaces between neurons exhibit characteristics of autism spectrum disorders (Peça J et al. Nature. doi:10.1038/nature09965 [published online ahead of print March 20, 2011]). To study the behavioral consequences of mutations in Shank3, a gene that...
Clinicians treating infants or young children who require surgery face a number of difficult choices, often with limited evidence to guide their decision making. One emerging concern is whether some interventions, particularly anesthesia, may cause additional harm to these vulnerable patients....
M. L. HARRIS, M.D., CHICAGO As a result of the efforts of physicians, every state has enacted so-called medical practice acts, the ostensible purpose of which is to protect the people against ignorance and incompetence on the part of those who treat the sick. The majority of these medical...
To the Editor: In 2006, the Centers for Disease Control and Prevention (CDC) issued recommendations for routine human immunodeficiency virus (HIV) testing in health care settings with HIV prevalence of 0.1% or greater for all persons aged 13 to 64 years, regardless of risk.1 Central elements...
In Reply: The underlying theme of our article was that sarcoidosis is a multisystem inflammatory disease. The case presented accentuates 2 points: sarcoidosis is often not benign, resulting in severe end-organ damage, and many patients are intolerant to the adverse effects of corticosteroids and...
A noninvasive genetic test developed by researchers at the Howard Hughes Medical Institute and Stanford University in Stanford, Calif, could help physicians forego heart biopsy to monitor the health of a transplanted heart (Snyder TM et al. Proc Natl Acad Sci U S A. doi:10.1073/pnas.1013924108...
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