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The statement of hypotheses and choice of statistical tests in clinical trials that compare surgical with nonsurgical treatment are complicated by the likelihood of excess risk in the surgical group during the perioperative period but lower risk after that compared with the more uniform...
Elizabeth Shepard's H can be read and appreciated on many levels. An epistolary novel, it chronicles the mental condition and progress of a 12-year-old boy. The letters that comprise the novel are written by the principal characters, primarily parents, summer camp personnel, peers, the...
To the Editor.
—In his article on investigational treatments, Dr Eddy1 describes "the minimum evidence required to provide physicians and patients with the information they need to determine how the treatment will affect the patient's outcomes." In addition, he asserts that...
IN 1989, the World Health Assembly resolved to reduce measles morbidity by 90% and measles mortality by 95% by 1995, compared with disease burden during the prevaccine era.1 By 1996, the estimated incidence and death rates for measles worldwide were reduced by 78% and 88%, respectively.2...
A FEW YEARS ago, Andrew Herxheimer, FRCP, of the United Kingdom Cochrane Centre in London, England, became curious about the fine print in the many pharmaceutical advertisements that cite references to unpublished material, labeled "data on file," to support claims made in the ads. He...
Drs Stout and Yu have raised several important points about measures to eradicate legionellae from hospital water distribution systems.
The Hospital Infection Control Practices Advisory Committee recommends flushing each distal outlet on the water distribution system for at least...
The acknowledged (though not by Vesalius) artist who designed the woodblocks, Jan Stephen of Calcar, was a pupil of Titian. Done in pearwood, these blocks were sawed with the grain and cut with knives (ie, not engraved), which makes their beauty and detail the more remarkable. Their...
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