1 - 10 of 48 articles
Neuroimaging was revolutionized by the development of computed tomography (CT) and standard T1- and T2-weighted magnetic resonance imaging (MRI). Magnetic resonance imaging and CT can adequately distinguish hemorrhage from infarction and depict ischemic stroke 12 to 24 hours after onset....
—We appreciate the comments generated by our report of a patient with chaparral-induced hepatotoxicity who required treatment with liver and kidney transplantation. All of the respondents called for increased precision in the use of terms referring to medications prepared from plants....
To the Editor.
—Drs Brophy and Joseph1 suggest that GUSTO2 does not directly address which thrombolytic strategy is superior and that the large sample size used enabled a statistically significant but not clinically meaningful difference to be detected. Using a Bayesian analysis, they conclude...
When I first agreed to review software for the Journal of the American Medical Association, I was skeptical of the applicability of what would arrive. For three years I have undertaken a search for educational medical software. I began using computers in 1982 and have used them in all phases of...
—We agree with Dr Avins that clinical significance is far more relevant to the interpretation of clinical trial results than statistical significance. However, it must be emphasized that our Figure 4 displays the posterior probability density for the difference in mortality rates...
—To compare and analyze the cost-effectiveness of different mammographic screening strategies.
—A computer simulation model was developed to compare mammographic screening with observation without screening. Cost-effectiveness was expressed as marginal cost per year of life...
To the Editor.
—Dr Le Gall and colleagues1 provided customized versions of the Simplified Acute Physiology Score II (SAPS II) and the 24-hour Mortality Probability Model II (MPM II24) to establish the probability of mortality for intensive care unit (ICU) patients with early severe sepsis. On...
To the Editor.
—The article by Drs Brophy and Joseph1 is a valuable contribution to the realistic appraisal of clinical trial evidence. Apart from the Bayesian perspective, however, the article highlights a critical problem with the traditional approach to hypothesis testing. The difficulty...
The teaching of anatomy has entered a whole new realm since the onset of the computer age and advances in diagnostic imaging. The videodisc-format Animations of Thoracic Viscera, part of the Digital Anatomist Videodisc Series from the University of Washington School of Medicine, represents a...
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