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Tacrine (tetrahydroaminoacridine, THA) was first available in Australia in the mid 1940s when it was used with morphine to lessen respiratory depression without affecting analgesia.1 Its anticholinesterase activity eventually led to clinical trials in patients with presumptive Alzheimer's...
—To review the studies on diagnostic evaluation of syncope and to provide an approach to the diagnostic testing and management of this condition.
—Published studies on the evaluation of syncope in the English language.
—Cohort studies and case series...
SOME CREDIT the aging of the "baby boomers" for the recent explosion of interest in menopause, a subject formerly treated with intense neglect.
The large number of women who were born in the decade following World War II are now approaching the age of last menses. In the next two decades,...
To the Editor.
—I read with interest the data presented by Sosin and Sacks1 regarding motorcycle helmet-use laws. I found the data particularly interesting in that the lower rate of death due to head injury was countered by a higher crash rate, resulting in comparable overall death rates.
Abstract In Reply. —Dr Winkelstein raises the possibility of selection bias in our analysis of CD4 lymphocyte decline in the ALIVE cohort of IVDUs. This bias must always be a serious concern in any longitudinal study; for this reason and because the decline in CD4 lymphocytes in our cohort of...
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