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A SYNDROME of apparently healthy infants dying suddenly and inexplicably was described almost a century ago and has been the subject of systematic study for more than 40 years. But understanding of crucial aspects of sudden infant death syndrome (SIDS)—what causes it, which infants are at risk,...
GENERIC DRUGS, the favored child of medical care cost cutters, have come under suspicion following revelations that some manufacturers may have engaged in dubious manufacturing and testing practices and about the bribing of Food and Drug Administration (FDA) employees. The Inspector General's...
THE MOST EXHAUSTIVE gene hunt in the history of molecular medicine came to an end September 8 with the publication of the identity of the cystic fibrosis (CF) gene (Science. 1989; 245:1059-1080).
The isolation of the gene brought not only knowledge of the function of the protein for which it...
THE INDENTIFICATION of the cystic fibrosis (CF) gene earlier this month culminated one of the most concerted and competitive efforts in the history of medical genetics.
Cystic fibrosis' high incidence (one in 2000 births in the United States), severity, and resistance to prenatal diagnosis has...
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