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In Reply. —
Drs Cooper and Griffith correctly point out that the drowning rates presented in our article were based on place of occurrence, not on place of residence. We do not believe, however, that this implies our rate calculations were "erroneous." The detailed information regarding...
To the Editor. —
We read with interest the article by Quinn et al1 about the rapid latex agglutination assay for antibody to HIV, but feel that their conclusions are not justified by the data. There were significant differences between the two test groups. The claimed 100% specificity and 99.3%...
In a prospective, randomized, double-blind clinical trial, intravenous prochlorperazine edisylate (Compazine Edisylate) was compared with a placebo in the treatment of severe headaches. Eighty-two adult patients with vascular or tension-type headaches were identified at the time of presentation...
The fact that most insurance contracts explicitly exclude the patient-care costs of clinical trials of investigational agents is an important disincentive for physicians and patients to participate in trials. The extent to which insurance companies enforce the research exclusion is...
To the Editor.—
The article entitled "NCI Seeks to Boost Study Participation"1 in the September 9 issue ignores the major reason that I as a community oncologist do not participate in clinical trials. The financial burden to the patient or their insurance company is a problem largely ignored by...
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