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To the Editor.—
The article from the Council on Scientific Affairs1 on handling parenteral antineoplastic agents was timely and well written. However, in discussing the risk of leukemia developing in patients with Hodgkin's disease who have been exposed to alkylating agents and procarbazine, a...
Hair samples from two healthy teenagers were sent under assumed names to 13 commercial laboratories performing multimineral hair analysis. The reported levels of most minerals varied considerably between identical samples sent to the same laboratory and from laboratory to laboratory. The...
To the Editor.—
I read with considerable interest the editorial by Dr Peter P. Morgan1 entitled "Randomized Clinical Trials Need to be More Clinical." I was somewhat amazed with the author's comment that a "randomized clinical trial requires clinicians to set aside their own judgments, asks...
DIABETIC ketoacidosis is a relatively simple diagnosis in a patient known to have diabetes, yet the differential diagnosis on the initial presentation of a new patient includes all the standard causes of an elevated anion gap acidosis.1 In a patient with severe anion gap acidosis, hyperglycemia,...
To the Editor.—
Drs Yarbro and Mortenson in their COMMENTARY in the Feb 1 issue of JAMA1 have correctly identified a critical issue in the care of cancer patients. Unfortunately, they did not stress that many of those patients who are in formal clinical trials are there precisely because the...
To evaluate the impact of the percutaneous removal of renal calculi we compared 41 patients who had undergone open renal surgery to 88 patients who had a one- or two-stage percutaneous nephrostolithotomy for symptomatic urolithiasis. The two groups were similar with regard to stone size, stone...
This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Medical educators and popular writers have ignored the topics of death and bereavement during most of the 20th-century revolution in medical technology...
ACCIDENTAL death, characterized as the neglected disease of modern society,1 is the leading mortality cause for persons 1 through 39 years of age and the third for those of all ages.2
Because of the medical, social, and economic implications of trauma, attention is increasingly focusing on a...
Even if the treatments being compared are equivalent, randomized allocation must be substituted for any preference the physician might have for a particular treatment in a given patient: hence, "judgment is set aside." The word "substandard" may be a little strong; however, if one of...
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