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From its modest beginning as a metabolite of a newly discovered fungus from Norway, cyclosporine has made its way steadily to medical prominence as the prototype of a new generation of immunopharmacologic agents.
"It must be pointed out that cyclosporine is no panacea," says immunologist Jean F....
Cyclosporine has not only virtually revolutionized the field of organ transplantation, but it may have other useful actions. Among the newest discoveries about this powerful agent, which apparently are unrelated to its effects on the immune response, are its antiparasitic effects.
"It is nothing short of amazing that we've come this far in the field of organ procurement and transplantation with such spotty, incomplete data as our base... we can't be sure if we have a true organ shortage or if we simply haven't been able to systematically procure the organs that may be...
Liver transplantation is no longer an "experimental" procedure but a therapeutic one, panelists at a consensus development conference held recently at the National Institutes of Health agreed. The group noted that more than 540 liver transplants have been done in four medical centers in the...
Simultaneous radiotherapy and chemotherapy may be useful in the treatment of both limited small-cell lung cancer and advanced Hodgkin's disease, according to reports presented at the recent meeting of the American Society of Clinical Oncology in San Diego.
This adds to the evidence already...
On page 3004 of the June 10 issue, a drawing accompanying an article on suction-assisted lipectomy featured structures identified as "fibrous septae." That last word should have been septa.
This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In the June 10 MEDICAL NEWS story on the link between human papilloma virus and cancer (1983; 249:2998), one photo caption should have read, "Abnormal...
Doxorubicin hydrochloride and daunorubicin hydrochloride, two of the most potent drugs in the anticancer arsenal, share, in addition to bone marrow suppression, another serious—sometimes fatal—adverse effect: cardiotoxicity. Recently, however, research at several institutions has begun to yield...
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