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The first antiviral agent licensed by the Food and Drug Administration for systemic use in the United States (October 1966) was amantadine hydrochloride, an agent that blocks infection by influenza A (and some influenza B) strains.
Yet, as recently as the influenza A epidemic of 1980, says R....
When amantadine hydrochloride was first licensed by the Food and Drug Administration in 1966, it was specified for prophylaxis of Asian influenza. Many who have watched amantadine's tortuous path to widespread acceptance believe a basic problem lay in this initial licensing.
"Soon after the...
One of the many complications of severe head trauma is heterotopic ossification (HO), the formation in various parts of the body of new bony masses in tissue (such as muscle) that usually does not calcify. Prophylactic treatments such as active and passive motion, splinting, anti-inflammatory...
Medical imaging's centennial is about a decade away, but there is much to celebrate already. More information is being extracted from more body areas for more purposes than ever before.
For the most part, the imaging equipment and techniques used to study the CNS (see last week's JAMA MEDICAL...
After a 25-year career with the American Medical Association, Joe D. Miller—who retired Dec 1 as senior deputy executive vice-president—is hardly out of action.
True, Frankfort, Ky, has replaced Chicago as his main hub of activity. He and his wife Mary now live there, not far from his birthplace...
To the Editor.—
The article by Sachs et al entitled "Reproductive Mortality in the United States," which appeared in The Journal (1982;247:2789) could be misleading to a reader on a few important points. For example, the article implied that the number of reproductive deaths would be reduced by...
Drs Rosenfield and Cushner make a number of useful comments that help the reader correctly interpret our analysis of reproductive mortality in the United States. They also say our article implied that the number of reproductive deaths may be reduced by half if women stop using oral...
To the Editor.—
The MEDICAL NEWS description of thermography (1982; 247:3296) contained some crucial errors in interpretation and fact. It pointed to the usefulness of thermography in musculoskeletal conditions but was not entirely accurate by implying that thermography can serve as an...
To the Editor.—
The recent article in The Journal (1982;247:835) by the Centers for Disease Control (CDC), Atlanta, regarding their second toxic shock syndrome (TSS) case-control study also discussed the results of our Tri-State Toxic Shock Syndrome Study (TSTSSS).1 We believe some of their...
We would like to thank the TSTSSS participants for their comments. However, the assertion that we have misinterpreted either our results or those of the TSTSSS is unwarranted. Both studies demonstrated clearly that, after taking absorbency into account, use of Rely brand tampons was...
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