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Serum samples from patients with erythema multiforme (EM) were examined for the presence of herpes simplex virus (HSV) antigen in immune complexes using the Raji cell radioimmunoassay. Raji-cell-bound immune complexes from eight of 12 patients with EM after HSV infection and four of four...
To the Editor.—
Two cases of fatal aplastic anemia following the use of topical ocular chloramphenicol have been recently reported.1,2 Regardless of dosage, systemic chloramphenicol can cause an idiosyncratic, usually fatal, hemopoietic event, with an incidence rate of one in 30,000 to 50,000...
Acute Renal Failure Defined
The term acute renal failure can be used for any situation in which the patient's BUN and creatinine levels rise. However, I favor a more restrictive use of the term for situations in which the rise in BUN and creatinine levels are not reversible immediately by...
Drug Treatment of Respiratory Diseases is the latest in the growing series of books devoted to the pharmacology of the airways. Essentially aimed at the same audience, these books vary in size, number of contributing authors, and emphasis on basic pharmacology. This single-authored book was...
To the Editor.—
The recent article by Eckardt et al (1981;246:2707) has a serious flaw in the selection of controls. A control group can be defined as identical to the test group in all respects except for absence of the one factor being studied, in this case, alcoholism. In their study, at...
It has long been an irritation to me that, after a patient experiences contrast media "reactions," physicians or other paramedical personnel will advise him never again to allow radiographic contrast agents—dyes, if you will— to be injected into him.
As a diagnostic radiologist, I have recently...
We compared the adverse reaction rates and antibody responses when influenza and pneumococcal vaccines were given simultaneously and separately. We used a double-blind, placebo-controlled protocol in which the participants, healthy university students and staff between 18 and 26 years of age,...
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