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A decade ago, the remarkable property of the newly discovered restriction enzymes, namely, their ability to cleave doublestranded DNA at particular base sequences, was widely regarded as a microbiological curiosity and of little practical utility. The short-sightedness of this view was rapidly...
This short volume attempts to assist the practicing physician and the physician in training with recognition and management of bone and joint diseases in elderly patients. With an ever enlarging older population, such an emphasis is welcome. However, in many instances, the only difference...
To the Editor.—
We would like to report the use of naloxone (Narcan) in the reversal of coma and apnea in a child who had ingested an unknown quantity of clonidine (Catapres).
Report of a Case.—
A 16-month-old, 9-kg girl was found by her mother with an open bottle of clonidine. A tablet of...
Plasma high-density lipoprotein (HDL)-cholesterol and lipid levels were measured in 12 male marathon runners (mean age, 40 years) who ran an average of 28 km/day for ten days, rested 70 hours, then continued to run for eight more days, covering a total distance for both running periods of 500...
Reading this informal survey was an unsettling experience—not because of any innate faults in the text, but because it brought to mind my own circumstances only recently resolved. It is widely recognized that residents—and this reviewer was no exception—are frequently inadequately prepared to...
To the Editor.—
In a recent article in The Journal (1980;244:2762), Carsky et al described the epicardial fat pad sign (EFPS) in the diagnosis of pericardial effusion. In another article1 they reported that 52% of 100 patients with echocardiographic evidence of pericardial effusion had positive...
In the absence of a positive family history for hereditary angioedema (HAE), both siblings in a family were found to have clinical and laboratory findings similar to those in HAE. Both siblings became symptom free after receiving danazol treatment, accompanied by a subnormal rise in C1 esterase...
Dr Keshgegian's point is valid and well taken. Although a correlation between the albumin concentration and anion gap would be expected, our study included patients with a narrow range of albumin values. With a wider range of albumin concentrations, say 1.0 to 5.0 g/dL, a positive...
ACUTE bilateral adrenal hemorrhage has been reported in postoperative patients,1 in patients with hemorrhagic diatheses,2,3 and in association with severe stress and hypotension.4 The diagnosis is considered infrequently before death because symptoms may be masked or ascribed to more common...
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