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CLINICAL pharmacology has grown out of a need to extend the discipline of basic pharmacology into clinical practice. A similar evolution of a clinical science took place when clinical pathology became established as a discipline separate from basic pathology. The progenitors of clinical...
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To the Editor.—
The daily rates of amino acid excretion by a cystinuric man with transplanted kidneys, first described in a letter (239:1132, 1978), have been remeasured recently, and, once again, have been found to be within the normal range (Table). Now 29 years old and 3 1/2 years after the...
To the Editor.—
The article by Hanson and Zimmerman (242:154, 1979) points to a new aspect of an old problem now appearing on the clinical scene, heatstroke. The present problem is with the young and healthy who collapse on hot and humid days while fun running.
As we have shown1 such incidents...
THERE is an intense and active debate concerning the need for board certification among the three major societies that represent clinical pharmacology. In fact, a task force composed of members of the American College of Clinical Pharmacology (ACCP), the American Society for Clinical...
Autopsy evidence of herpesvirus infection was found in visceral organs of four leukemic patients who had received large doses of cytarabine (cytosine arabinoside; Ara-C) shortly before their death. In three of these patients the infection was clinically unsuspected; in the fourth, cutaneous...
To the Editor.—
In the letter on Tietze's syndrome by Carl Jelenko III, MD (242:2556, 1979), he claims he described the "first reported cases of Tietze's syndrome affecting the xiphisternal joint" in 1974. Current Therapy, 1967 (Philadelphia, WB Saunders Co), page 108 has an article, "Rib...
Adverse reactions to cimetidine have been identified through the manufacturer's Worldwide Spontaneous Reporting System. Reactions not observed during clinical trials—mental confusion, interstitial nephritis, and potentiation of oral anticoagulants—were identified and added to the prescribing...
This book, first published in French in 1978, has been translated into English to reach a wider audience. The authors summarize their vast experience at the Hôpital de Bicêtre, Université Paris Sud in pediatric hepatology. It is one of the first two English language textbooks devoted to this...
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