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Tracing the rise and fall of drug molecules in the human body is beginning to pay off. Consider cardiology, where pharmacokinetic studies have already provided the clinician with practical guidelines for optimal dosing with lidocaine; now we learn that tissue levels of procainamide...
THE PENICILLINASE-RESISTANT penicillins are effective, highly specific agents for treatment of staphylococcal infections. Accordingly, there must be strong evidence that the patient does have staphylococcal infection and that it is sensitive to this class of drugs. Parenteral therapy with these...
To the Editor.—
Dr Mays' timely COMMENTARY on the standard nomenclature for primary hepatic tumors contained several important inaccuracies. He suggested that our recent article1 is, in part, responsible for the confusion surrounding this subject. In fact, our article included a review of the...
Eight patients with parotid enlargement were seen because of varying musculoskeletal complaints. All were overweight and hypertensive; six had diabetes mellitus, four had palpable hepatomegaly, and six were 49 years or older. One patient had arthritis type IIB hyperlipoproteinemia. Four patients...
The editors of a medical dictionary face colossal problems: new terms to be listed, obsolete terms eliminated, current meanings revised where necessary, synonyms noted and cross-referenced. Someone must decide on the scope and overall coverage, the illustrations to be replaced or added, the...
This text is a product of the faculty of the Department of Ophthalmology, University of Florida, Gainesville. Most of the faculty who have contributed to this journal are contemporary or past members of this program. The authors have not attempted to make this a standard textbook or source of...
To the Editor.—
Dr Browning's article "Handguns and Homicide" (236:2198, 1976) brings to mind Dr Ingelfinger's "Seduction by Citation" in the New England Journal of Medicine (295:1075-1076, 1976). Certainly there are many, including myself, who would question the statistics that Dr Browning...
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