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Myoglobin was detected in the sera of patients with dermatomyositis, polymyositis, scleroderma, and systemic lupus erythematosus (LE) with active myopathy. Overall, myoglobinemia was detected in 74.1% of sera taken from patients with active myositis before therapy, with slightly greater...
IT HAS recently been reported1 that, among patients undergoing mammography at a hospital in Detroit, the prevalence of breast cancer was higher in women receiving thyroid hormone therapy than in those who were not. Prevalence of breast cancer was said to increase with increasing duration of...
THE THERAPEUTIC range of plasma concentrations of the antiasthmatic drug theophylline is relatively narrow (approximately 10 to 20μg/ml). It is difficult to design safe and effective dosage regimens for this drug without monitoring plasma concentrations because of the pronounced interindividual...
To the Editor.—
This letter refers to the article "Pharmacokinetic Approach to the Clinical Use of Lidocaine Intravenously" (236:273, 1976) by Greenblatt et al. I would like to call attention to a possible problem with the data on which they base their approach.
Greenblatt and colleagues base...
We thank Dr Kumar for his comments, particularly those emphasizing the importance of noninvasive techniques in the evaluation of the postinfarction patient. We did not, as Dr Kumar states, review the role of apexcardiography in our succinct section on noninvasive techniques;...
To the Editor.—
One of the most common hospital procedures is the use of the lowly nasogastric (NG) tube. As all physicians who use NG tubes know, nasal irritation and ulceration are common complications. Sinusitis, serous otitis, and pharyngitis are also commonly seen.
I recently intubated a...
This book emanates from a neurosurgical center with considerable experience in the chemotherapeutic management of malignant brain tumors. The dust jacket advertises the book as not only presenting the concepts underscoring the strategy of chemotherapy for primary malignant tumors of brain, but...
Brilliant illumination of obscure cardiac diagnoses by invading the heart with catheter and contrast materials may seem to cast into shadows the classical modes of inspection, palpation, percussion, and auscultation. Actually, however, from these shadows now comes a greater and more reliable...
To the Editor.—
It is unfortunate that Drs Melicow and Uson do not favor needling benign renal cysts (236:2546, 1976). Cyst puncture combined with pathologic examination of the aspirate is a simple, safe, and extremely accurate method of differentiating a benign renal cyst from renal carcinoma....
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