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Absorption Rates Vary
Brand, Generic Drugs Differ In Man
Comparison of brand and generic forms of three drugs, tested in healthy volunteers, shows several significant differences in amount and rate of absorption, investigators at...
Following prelabeling of the albumin space by iodinated I 131 serum albumin, six normal ambulatory male volunteers were phlebotomized 15% to 20% of blood volume to characterize their response to phlebotomy. Blood volume, as reflected by serial determinations of hematocrit values, was...
A new, high-potency, glycine-precipitated antihemophilic factor (AHF, factor VIII) concentrate, from 100 to 400 times purified, can be administered to patients in solutions 100 times more concentrated than plasma. The product appears to be stable and causes no immediate untoward side...
The clinical features of the pigmentation in 27 cases of Albright's syndrome and 19 cases of neurofibromatosis were indistinguishable. Microscopic study of split-skin preparations showed giant pigment granules in malpighian cells or in melanocytes, or in both, in normal skin and in...
A study was performed at the Hartford Hospital to determine the value of routine screening electrocardiography in an outpatient population. Screening electrocardiograms were abnormal in 1,197 of 2,924 cases (40.9%). Dependence upon physician request or upon a positive response to a...
Local and systemic administration of certain drugs has resulted in many forms of visual complications. These include blurred vision, disturbances in color vision, scotomata, pigmentary degeneration of the retina, and damage to the cornea, retina, and optic nerve. The drugs responsible...
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