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THE SAFETY ASSESSMENT of a drug relates its usefulness for an intended purpose to its inherent manifestations of toxicity; any useful drug can be shown to cause some undesirable effects in man or animal if searched for adequately. Thus, following the election of a new compound for...
Estimation of renal function utilizing the excretory urogram is generally unsatisfactory, except when judged from early films. By comparing the specific gravity of urine specimens obtained just prior to the administration of the contrast medium and prior to the postvoiding film, the...
The transient recurrent attack of binocular blurring of vision, one of the most frequent symptoms of insufficiency of the vertebrobasilar arterial system, may be a forerunner of stroke. Diagnosis and understanding of the mechanisms underlying these attacks are necessary if preventive...
PSYCHOSIS that occurs during quinacrine hydrochloride administration has long been recognized as an infrequent but important toxic manifestation of this drug. It has only recently been noted that a toxic psychosis can be produced by chloroquine phosphate.
Two patients have been...
Although John Radcliffe made no significant L literary or scientific contributions to medicine, his philanthropic gifts to Oxford and London will survive throughout the centuries. He came of humble origin, rose to an enviable position in English medicine as physician to the royal family,...
JAUNDICE secondary to unilateral hepatic duct obstruction is a rarity. Usually associated are cholochromatic stools (containing bile pigment), amber urine, normal liver flocculations, and enlargement of the homolateral liver lobe.
Seven cases of unilateral hepatic duct...
"There is an involuntary conspiracy in the United States to bury the physician beneath a deluge of charts, forms, and other paper work," according to Carl F. Baumeister, MD, of the department of internal medicine at MacNeal Memorial Hospital and the Suburban Medical Center in Berwyn,...
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