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Key PointsQuestionDoes early postoperative acetaminophen exposure reduce the incidence of acute kidney injury in children who undergo cardiac surgery?
FindingsIn this cohort study, acetaminophen exposure in the first postoperative 48 hours was associated with a lower rate of acute kidney injury...
Key PointsQuestionIs exposure to diethylstilbestrol during pregnancy associated with adverse multigenerational neurodevelopmental outcomes?
FindingsA cohort study of 47 450 women in the Nurses’ Health Study II found significantly elevated odds for attention-deficit/hyperactivity disorder in the...
This study describes the incidence rates for 4 lysosomal storage disorders from 4 years of full-population testing of all newborns in Missouri.
ImportanceThe effect of neonatal and infant feeding practices on childhood obesity is unclear. The gut microbiome is strongly influenced by feeding practices and has been linked to obesity.
ObjectiveTo characterize the association between breastfeeding, microbiota, and risk of overweight during...
Key PointsQuestionIs vitamin D supplementation during pregnancy beneficial and safe for offspring?
FindingsIn this systematic review and meta-analysis of 24 randomized clinical trials including 5405 individuals, vitamin D supplementation during pregnancy was associated with a lower risk of...
Key PointsQuestionDoes the duration of preprocedural fasting alter the risk pulmonary aspiration and associated adverse outcomes in children undergoing emergency department procedural sedation?
FindingsIn this study of 6183 healthy patients undergoing sedation in 1 of 6 geographically separate...
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