1 - 10 of 36 articles
ImportanceThe in vivo effect of pilocarpine hydrochloride on the Schlemm canal may help explain its pharmacologic mechanism of action and better indicate its clinical use.
ObjectiveTo investigate the effect of pilocarpine on the structure of the Schlemm canal in vivo in healthy eyes and eyes...
ImportanceMinimally invasive glaucoma surgical (MIGS) devices are one option for lowering intraocular pressure in patients with glaucoma.
ObjectiveTo examine how often existing clinical studies of MIGS devices registered on ClinicalTrials.gov measure patient-centric outcomes that patients value...
This cross-sectional study compares measures of central corneal thickness in patients with keratoconus and normal corneas using in vivo confocal microscopy, ultrasonic pachymetry, and Scheimpflug topography.
ImportanceA multiorgan syndromic disorder characterized by sideroblastic anemia, immunodeficiency, periodic fever, and developmental delay with an uncharacterized retinal dystrophy is caused by TRNT1. This report of a family with a homozygous mutation in TRNT1 expands the ocular phenotype to...
An otherwise healthy woman in her 50s presented with blurry vision in both eyes after a routine eye examination with dilation 5 days earlier. The pupils were middilated and poorly reactive, and the lenses were displaced into the anterior chambers without any lenticular zonules visible. What...
Key PointsQuestionIs in vivo confocal microscopy a good tool to evaluate small fiber alterations in familial amyloid polyneuropathy (FAP)?
FindingsThis cross-sectional controlled pilot study revealed that corneal nerve fiber length (CNFL) was shorter in 15 patients with FAP than in controls....
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