1 - 10 of 25 articles
Within 20 years of its discovery 100 years ago, vitamin A was recognized as critical to normal eyes, growth, and survival. Clinical interest subsequently contracted to its importance in preventing xerophthalmia, until this ophthalmologist stumbled, quite accidently, on its role in fighting...
ImportanceWe report for the first time, to our knowledge, the acquisition of noncontact ultra–wide-field oral fluorescein angiograms in premature infants with retinopathy of prematurity.
ObservationsHigh-resolution oral fluorescein angiograms were successfully obtained in 3 consecutive premature...
Mission Statement: To be the indispensable source of ophthalmic knowledge by promptly publishing innovative, clinically relevant research through consistent and authoritative peer review and; thereby, to be the first choice of authors for their important manuscripts. Editor: Neil M. Bressler, MD...
ImportanceChildren with optic pathway gliomas (OPGs) frequently experience vision loss from their tumors. Standard front-line treatment using carboplatin-based chemotherapy typically produces only a modest benefit (eg, stabilization or 0.2 logMAR improvement) in visual acuity (VA). Bevacizumab...
ImportanceThe potential association between age-related macular degeneration (AMD) and Alzheimer disease (AD) is uncertain and has implications for understanding disease pathogenesis, referral, and treatments.
ObjectivesTo determine whether individuals admitted to the hospital with AMD were...
ImportanceInhibition of inflammatory cytokines may have therapeutic effects in diabetic retinopathy (DR).
ObjectiveTo compare aqueous and vitreous levels of 17 inflammatory cytokines in patients treated preoperatively with topical ketorolac tromethamine, 0.45%, or placebo before pars plana...
ImportanceUnderstanding the natural history of visual outcome in branch retinal vein occlusion (BRVO) is fundamental to its management.
ObjectiveTo investigate the natural history of visual outcome in major and macular BRVO.
Design, Setting, and ParticipantsObservational cohort study at a...
Research Common Mechanisms Underlying Refractive Error Few genes have been identified that lead to refractive error in the general population. To identify genes moderately associated with refractive error, Hysi and colleagues analyzed genome-wide association studies in 2 British population-based...
ImportanceTo date, relatively few genes responsible for a fraction of heritability have been identified by means of large genetic association studies of refractive error.
ObjectiveTo explore the genetic mechanisms that lead to refractive error in the general population.
Design, Setting, and...
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