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This Viewpoint describes the implications of US Food and Drug Administration changes to postmarketing requirements.
Key PointsQuestionWhat are the trends in life expectancy and cause-specific late mortality after allogeneic blood or marrow transplantation over a 40-year period?
FindingsThis cohort study of 4741 individuals 2 years after allogeneic blood or marrow transplantation performed between 1974 and...
This retrospective cohort study examines the risk factors and predictors of second primary cancers after being diagnosed with neuroendocrine tumors.
This cross-sectional study examines atezolizumab as a second-line treatment for malignant urothelial carcinoma, which received accelerated US Food Drug Administration approval, although the manufacturer’s confirmatory trial did not identify benefits.
This retrospective case series study examines immune response of adults with hematologic malignant disease who were vaccinated with 1 of 3 FDA-authorized COVID-19 vaccines between February and April of 2021.
A 33-year-old woman with a history of hereditary bilateral retinoblastoma as an infant presents with 1 week of right lower extremity swelling. What is your diagnosis?
Key PointsQuestionWhat are the prognostic implications of luminal and basal subtypes in metastatic castration-resistant prostate cancer?
FindingsIn this cohort study including tissue samples from 634 patients with metastatic prostate cancer, distinct molecular patterns associated with luminal...
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