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This Patient Page describes the use of circulating tumor DNA testing to detect cancer-associated genetic variations and guide treatment recommendations.
This Viewpoint explores the use of molecular predictors of therapeutic responsiveness in assessing risk for patients with metastatic renal cell carcinoma.
In this essay, the author describes a magnifying glass, given to him by his mentor, that becomes for him the symbol of blocking out all distractions to view with focused intent the primary importance of the patient’s well-being in the practice of medicine.
This Viewpoint describes infection prevention and control measures implemented in the care of patients with cancer during the COVID-19 outbreak in China.
Key PointsQuestionWhat is the frequency of pathogenic or likely pathogenic germline genetic variants in known cancer-susceptibility genes in a large population of patients with osteosarcoma who were unselected for family history?
FindingsIn this next-generation exome sequencing study of 1244...
Key PointsQuestionFor men with recurrent prostate cancer after radical prostatectomy, can prostate-specific antigen (PSA) level be used to help predict outcomes of long-term antiandrogen treatment added to salvage radiotherapy (SRT)?
FindingsIn this secondary analysis of the RTOG 9601 trial,...
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