1 - 10 of 43 articles
This Viewpoint provides an evaluation of partial breast irradiation as an alternative to standard and hypofractionated whole-breast irradiation in terms of its ability to reduce duration of treatment and provide equivalent outcomes, comparable or reduced adverse effects, and cost-effectiveness
This review outlines the rationale and preclinical evidence that support immune checkpoint inhibitor plus targeted therapy combination and sequencing strategies in melanoma and highlights results from clinical trials exploring these approaches.
This Viewpoint describes 3 issues to be considered before upcoming US Food and Drug Administration reviews of electronic cigarette products.
Key PointsQuestionDoes site-specific treatment, including molecularly targeted therapy based on profiling gene expression and gene alterations by next-generation sequencing, have clinical use for patients with cancer of unknown primary site?
FindingsThis phase 2 nonrandomized clinical trial of...
Key PointsQuestionWhat is the efficacy of weekly paclitaxel, with or without bevacizumab, as treatment for relapsed sex cord-stromal tumors?
FindingsIn this randomized clinical trial including 60 women with relapsed sex cord-stromal tumors, adding bevacizumab to weekly paclitaxel did not improve...
This cohort study evaluates the national practice patterns of MGMT gene testing and identified potential factors associated with access to testing.
Key PointsQuestionWhat is the spectrum of multisystem immune-related adverse events (irAEs) that occur in patients with non–small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors (ICIs)? Do patients with multisystem irAEs have improved survival, adjusting for treatment...
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