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This randomized clinical trial of patients with stage I gastric cancer examines whether long-term survival among patients undergoing laparoscopic distal gastrectomy is noninferior to that among patients undergoing open distal gastrectomy.
This study assesses the outcomes of single-patient use of the US Food and Drug Administration Expanded Access program.
ImportanceApproximately 50% of the risk for the development of testicular germ cell tumors (TGCTs) is estimated to be heritable, but no mendelian TGCT predisposition genes have yet been identified. It is hypothesized that inherited pathogenic DNA repair gene (DRG) alterations may drive...
This nationwide, population-based cohort-cohort study of compares the temporal pattern of hospitalizations for medically verified incident somatic disease between cancer survivors and cancer-free people.
This Viewpoint highlights the importance of potential bias in patient-reported outcomes in open-label cancer trials and points to areas of research that could address this challenge.
ImportanceAcross many countries, a rapid escalation of the incidence of thyroid cancer has been observed, a surge that nonetheless underestimates the true extent of the disease. Most thyroid cancers now diagnosed comprise small, low-risk cancers that are incidentally found and are unlikely to...
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