1 - 10 of 34 articles
Key PointsQuestionDoes local control of brain metastases differ between treatment with surgical resection vs stereotactic radiosurgery?
FindingsIn this exploratory analysis of the European Organization for the Research and Treatment of Cancer 22952-26001 trial including 268 patients with brain...
Key PointsQuestionFor metastatic colorectal cancer, what is the incremental cost-effectiveness of adding capecitabine and bevacizumab maintenance treatment after standard induction chemotherapy?
FindingsThis economic evaluation study finds that compared with observation, capecitabine and...
This Viewpoint analyzes data on the thrombotic risk associated with cyclin-dependent kinase inhibitors and notes the need for additional research on the thrombotic risk of these drugs, the influence of combined drug therapy on thrombotic risk, and patient selection.
This Viewpoint discusses the initials results of the NCI-MATCH trial, a phase 2 study that seeks to determine whether targeted therapies for specific gene mutations will lead to objective responses agnostic to the primary cancer type.
This population-based study describes the incidence, latency period, and outcomes of radiotherapy-associated angiosarcoma among patients with breast cancer from the Netherlands Cancer Registry.
Key PointsQuestionWhat were 3-year outcomes with nivolumab vs dacarbazine in patients with previously untreated BRAF wild-type advanced melanoma?
FindingsIn this follow-up of a randomized phase 3 trial, 3-year overall survival rates for nivolumab and dacarbazine were 51.2% and 21.6%,...
An HIV-positive man in his 30s being treated with pembrolizumab for metastatic programmed cell death ligand 1–positive squamous non–small cell lung cancer presents with pruritic, mildly painful, hyperpigmented papules and plaques on both feet. What is your diagnosis?
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