1 - 10 of 36 articles
This study examines the association of diagnostic yield and postsurgical recurrence-free survival with restaging abdominopelvic computed tomography performed before surgery after receiving chemoradiotherapy in patients with locally advanced rectal cancer.
This Viewpoint examines the recent US Food and Drug Administration approval of pembrolizumab and its implications for precision oncology and tumor-type classifications.
Key PointsQuestionWould molecular imaging with positron emission tomography for androgen receptors using fluorodihydrotestosterone F 18 and glycolysis using 2-fluoro-2-D-deoxyglucose F 18 identify biochemical characteristics of castration-resistant prostate cancer that would be predictive for...
ImportanceIf not promptly recognized, endocrine dysfunction can be life threatening. The incidence and risk of developing such adverse events (AEs) following the use of immune checkpoint inhibitor (ICI) regimens are unknown.
ObjectiveTo compare the incidence and risk of endocrine AEs following...
Key PointsQuestionBased on data from the United Kingdom Collaborative Trial of Ovarian Cancer Screening, is multimodal screening (MMS) with serum cancer antigen 125 (CA-125) interpreted using a risk algorithm cost-effective?
FindingsMultimodal screening is both more expensive and more effective...
This Viewpoint explores the legislation that allows payment for wastage of injectable medications.
Key PointsQuestionDoes the American Joint Committee on Cancer eighth edition breast cancer prognostic stage provide more refined stratification with respect to disease-specific survival than the anatomic stage?
FindingsPatients with breast cancer treated with surgery as an initial intervention...
Key PointsQuestionIs treatment with inotuzumab ozogamicin plus low-intensity chemotherapy effective in relapsed or refractory acute lymphoblastic leukemia (ALL)?
FindingsIn a single-arm, phase 2 clinical trial of 59 adults relapsed or refractory ALL, the overall treatment response rate was 78%,...
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